Peel Off Mask Formulation of Red Dragon Fruit Extract (Hylocereus lemairei Hook.) and Corn Starch with Variation of Polyvinyl Alcohol (PVA) Concentration

Authors

DOI:

https://doi.org/10.36733/medicamento.v9i2.3576

Keywords:

corn starch, peel-off mask, polyvinyl alcohol, red dragon fruit

Abstract

Red dragon fruit is rich in nutrients and minerals as well as phytoalbumin and antioxidant compounds such as phenolic compounds and vitamin C. Corn contains vitamins A, B, and E as antioxidants, as well as Thiamin, which can reduce black spots on acne scars and dry out wounds. Peel-off masks are cosmetic preparations for facial care that can form a thin, transparent layer on the surface of the skin and can be peeled off after drying, so they are practical to use. Polyvinyl alcohol (PVA) is a film-forming polymer and can increase viscosity, which in turn plays a role in producing peel-off masks that have good physical quality. This study aims to formulate peel-off masks of red dragon fruit extract (Hylocereus lemairei Hook.) and corn starch with varying concentrations of PVA (F1:2.5%, F2:8.75%, F3:17.5%) in order to have a high-quality good physique. The evaluation of the physical quality of the red dragon fruit and corn starch peel-off masks was organoleptic, homogeneity, pH, spreadability, adhesion, and drying time. The organoleptic preparations (F1-F3) were brownish-orange in color, with a distinctive rose odor, with increased viscosity from F1 to F3, and remained stable for up to 4 weeks of storage. The homogeneity of preparation (F1-F3) was homogeneous and lasted for 4 weeks of storage. The pH value of the preparation on day 1, F1 and F2, had a pH of 4, and F3 had a pH of 4.5. From the 1st to the 4th week, the pH of preparations F1-F3 was 4.5, according to the physiological pH of the skin, 4-8. The spreadability of F1-F3 preparations was in the 5.5-6.5 cm range, according to 5-7 cm provisions. The adhesive power of the F1-F3 preparations was in the range of 5.29-40.1 seconds, which is recommended for more than 1 second. The drying time of F1-F3 preparations was in the range of 20.58-30.45 minutes, according to the provisions of 15-30 minutes. The three red dragon fruit and corn starch peel-off mask formulas (F1, F2, and F3) meet the requirements for good physical quality according to the criteria set and recommended. Increasing the PVA concentration did not affect the pH value and spreadability of the three formulas but increased the adhesiveness value and drying time.

Author Biographies

Ni Made Dharma Shantini Suena, Universitas Mahasaraswati Denpasar

Department of Pharmaceutics, Bachelor of Pharmacy Program, Faculty of Pharmacy

I Gusti Agung Ayu Kusuma Wardani, Universitas Mahasaraswati Denpasar

Department of Pharmacology and Clinical Pharmacy

Ni Putu Udayana Antari, Universitas Mahasaraswati Denpasar

Department of Social Pharmacy, Faculty of Pharmacy

References

Rittie L, Fisher GJ. Natural and Sun-Induced Aging of Human Skin. Cold Spring Harb Perspect Med. 2015;5(1):1-14. doi:10.1101/cshperspect.a015370

Chen J, Liu Y, Zhao Z, Qiu J. Oxidative stress in the skin: Impact and related protection. Int J Cosmet Sci. 2021;43(5):495-509. doi:10.1111/ics.12728

Rahul Simon Situmeang, Gim Mi Kyong, Rosiva Betaria Purba, Irawati W. Anti-PD-L1 Therapy as a Solution for Non-Melanoma Skin Cancer Basal Cell Carcinoma. BIOEDUSCIENCE. 2022;6(1):48-56. doi:10.22236/j.bes/618095

Sharma A, Kuhad A, Bhandari R. Novel nanotechnological approaches for treatment of skin-aging. J Tissue Viability. 2022;31(3):374-386. doi:10.1016/j.jtv.2022.04.010

Gilaberte Y, Prieto-Torres L, Pastushenko I, Juarranz Á. Anatomy and Function of the Skin. In: Nanoscience in Dermatology. Elsevier; 2016:1-14. doi:10.1016/B978-0-12-802926-8.00001-X

Lopez-Ojeda W, Pandey A, Alhajj M, Oakley AM. Anatomy, Skin (Integument). StatPearls Publishing; 2022. https://www.ncbi.nlm.nih.gov/books/NBK441980/

Karmilah K, Rusli N. Formulasi dan Uji Efektivitas Masker Peel Off Pati Jagung (Zea mays sacchrata) sebagai Perawatan Kulit Wajah. J Ilm Manuntung. 2018;4(1):59-66.

Fathordoobady F, Mirhosseini H, Selamat J, Manap MYA. Effect of solvent type and ratio on betacyanins and antioxidant activity of extracts from Hylocereus polyrhizus flesh and peel by supercritical fluid extraction and solvent extraction. Food Chem. 2016;202:70-80. doi:10.1016/j.foodchem.2016.01.121

Kumar S, Tripathi V, Kumari A, Chaudhary V, Kumawat P. A-review: on Nutritional and Medicinal Importance of Dragon Fruit (Hylocereus species). Ecol Environ Conserv. 2022;28:247-253. doi:10.53550/EEC.2022.v28i07s.041

Sari NR, Setyowati E. The Effect of Corn and Olive Oil Masks on Facial Skin Care [Pengaruh Masker Jagung dan Minyak Zaitun terhadap Perawatan Kulit Wajah]. J Beauty Beauty Heal Educ. 2014;3(1):1-7. https://journal.unnes.ac.id/sju/index.php/bbhe/article/view/7762

Bolke L, Schlippe G, Gerß J, Voss W. A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients. 2019;11(10):2494. doi:10.3390/nu11102494

Suarni S, Subagio H. Potential of Corn and Sorghum Development as Functional Food Sources. Litbang Pertan. 2013;32(1):2. doi:10.21082/jp3.v32n2.2013

Balić A, Vlašić D, Žužul K, Marinović B, Bukvić Mokos Z. Omega-3 Versus Omega-6 Polyunsaturated Fatty Acids in the Prevention and Treatment of Inflammatory Skin Diseases. Int J Mol Sci. 2020;21(3):741. doi:10.3390/ijms21030741

Nofriyanti N, Rianti R, Suhery WN, Agistia N, Muhtadi W khairi. Formulasi Dan Evaluasi Fisik Masker Gel Peel Off Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus). J Penelit Farm Indones. 2022;11(2):5-10. doi:10.51887/jpfi.v11i2.1741

Hamsinah H, Yahya SH, Ririn R. Formulasi Masker Peel off Ekstrak Etanol Kulit Buah Naga Merah (Hylocereus polyrhizus) Menggunakan Polivinil Alkohol (PVA). Media Farm. 2019;15(2):171-177.

Sevija FA, Larasati D, Nugraha MTA. Karakterisasi Fisik dan Uji Hedonik Masker Gel Peel-off Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus). J Kesehat Madani Med. 2022;13(02):305-314.

Sheskey PJ, Cook WG, Cable CG. Handbook of Pharmaceutical Excipients. 8th ed. (Sheskey PJ, Cook WG, Cable CG, eds.). Pharmaceutical Press and American Pharmacist Association; 2017. https://www.pharmpress.com/product/9780857113757/excipients

Asthana N, Pal K, Aljabali AAA, Tambuwala MM, de Souza FG, Pandey K. Polyvinyl alcohol (PVA) mixed green–clay and aloe vera based polymeric membrane optimization: Peel-off mask formulation for skin care cosmeceuticals in green nanotechnology. J Mol Struct. 2021;1229:129592. doi:10.1016/j.molstruc.2020.129592

Tanjung YP, Rokaeti AM. Formulasi dan Evaluasi Fisik Masker Wajah Gel Peel Off Ekstrak Kulit Buah Naga Merah (Hylocereus Polyrhizus). Maj Farmasetika. 2020;4(Suppl 1):157-166. doi:10.24198/mfarmasetika.v4i0.25875

Utami W, Mardawati E, Putri SH. Pengujian Aktivitas Antioksidan Kulit Buah Naga Merah (Hylocereus polyrhizus) Sebagai Masker Gel Peel Off. J Ind Pertan. 2020;2(1):95-102. http://jurnal.unpad.ac.id/justin/article/view/26181

Jani TA, Hakim A, Juliantoni Y. Formulation and Evaluation of Antioxidant Peel-Off Face Mask Containing Red Dragon Fruit Rind Extract (Hylocereus polyrhizus Haw.). J Biol Trop. 2020;20(3):438-445. doi:10.29303/jbt.v20i3.2157

Dewi IP, Tan V, Gani J. Uji Aktivitas Antioksidan Masker Peel-Off Ekstrak Etanol Buah Naga Super Merah. J Sains Farm Klin. 2019;6(1):1-6.

Ningsih W, Firmansyah F, Fitri H. Formulasi Masker Peel Off dengan Beberapa Konsentrasi Ekstrak Etanol Buah Naga Super Merah (Hylocereus costaricensis (F.A.C Weber) Britton & Rose). Scientia. 2016;6(1):18-24.

Setiawati R, Sukmawati A. [Karakterisasi Fisik dan Aktivitas Antioksidan Masker Wajah Gel Peel off yang Mengandung Sari Buah Naga (Hylocerus polyrhizus)] Physical characterisation and antioxidant activity of peel off gel face mask containing Hylocerus polyrhizus fruit juice. Pharmacon J Farm Indones. 2018;15(2):65-74.

Suena NMDS, Meriyani H, Antari NPU. Uji Mutu Fisik Dan Uji Hedonik Body Butter Maserat Beras Merah Jatiluwih. J Ilm Medicam. 2020;6(1):59-65. doi:10.36733/medicamento.v6i1.843

Pratiwi L, Wahdaningsih S. Formulasi dan Aktivitas Antioksidan Masker Wajah Gel Peel Off Ekstrak Metanol Buah Pepaya (Carica papaya L.). J Farm Medica/Pharmacy Med J. 2018;1(2):50-62. doi:10.35799/pmj.1.2.2018.21643

Suena NMDS, Ariani NLWM, Antari NPU. Physical Evaluation and Hedonic Test of Sandalwood Oil (Santalum album L.) Cream as an Anti-Inflammatory. J Ilm Medicam. 2022;8(1):22-30. doi:10.36733/medicamento.v8i1.3425

Priani SE, Irawati I, Darma GCE. Formulation of Mangosteen Peel off Skin Mask (Garcinia mangostana Linn.). Indones J Pharm Sci Technol. 2015;2(3):90-95. doi:10.24198/ijpst.v2i3.7905

Suena NMDS, Antari NPU, Cahyaningsih E. Physical Quality Evaluation Of Body Butter Formulation From Etanol Extract Of Mangosteen (Garcinia Mangostana L.) Rind. J Ilmu Kefarmasian Indones. 2017;15(1):63-69. Accessed July 13, 2021. http://jifi.farmasi.univpancasila.ac.id/index.php/jifi/article/view/455

Suena NMDS, Suradnyana IGM, Juanita RA. Formulasi dan Uji Aktivitas Antioksidan Granul Effervescent dari Kombinasi Ekstrak Kunyit Putih (Curcuma zedoaria) dan Kunyit Kuning (Curcuma longa L.). J Ilm Medicam. 2021;7(1):32-40. doi:10.36733/medicamento.v7i1.1498

Sekarsari S, Widarta IWR, Jambe AAGNA. Effect of Temperature and Time of Ultrasonic Wave Extraction on the Antioxidant Activity of Guava Leaf Extract (Psidium guajava L.) [Pengaruh Suhu dan Waktu Ekstraksi dengan Gelombang Ultrasonik terhadap Aktivitas Antioksidan Ekstrak Daun Jambu Biji (Psid. J Ilmu dan Teknol Pangan. 2019;8(3):267-277. doi:10.24843/itepa.2019.v08.i03.p05

Ainaro EP, Gadri A, Priani SE, Lendir PM, Achatina B, Bowdich F. Formulasi Sediaan Masker Gel Peel-Off Mengandung Lendir Bekicot (Achatina Fulica Bowdich) sebagai Pelembab Kulit. Pros Penelit Spes Unisba 2015. 2015;(2012):86-95.

Suhesti TS, Rohman MMH, Sunarto S. Formulation of Gel Hand Sanitizer of Nagasari Leaf Extract (Mesua ferrea L.). Indones J Pharm Sci Technol. 2022;1(1):31. doi:10.24198/ijpst.v1i1.36465

Adrianta KA, Yuda PESK, Purnamasari PS, Suena NMDS. Jackfruit (Artocarpus heterophyllus Lamk) Leaf as a Natural Sun Stick Protector Through the Inhibition of the MMP-1 Receptor. Trop J Nat Prod Res. 2023;7(5):2952-2958. doi:10.26538/tjnpr/v7i5.17

Fauziah F, Marwarni R, Adriani A. Formulasi dan Uji Sifat Fisik Masker Wajah Peel-off dari Ekstrak Sabut Kelapa (Cocos nucifera L.). J Ris Kefarmasian Indones. 2020;2(1):42-51. doi:10.33759/jrki.v2i1.74

Rani Z, Ridwanto R, Nasution HM, Kaban VE, Nasri N, Karo NB. Antibacterial activity of freshwater lobster (Cherax quadricarinatus) shell chitosan gel preparation against Escherichia coli and Staphylococcus aureus. J Appl Pharm Sci. 2022;13(2):146-153. doi:10.7324/JAPS.2023.130216

Wardani IGAAK, Jawi IM, Senapathi TGA, et al. The Effect of Xylocarpus granatum J. Koenig Seed Extract Cream on The Number of Fibroblast and Re-Epithelialization in IIA Degree Burn Wound Healing. Indones J Pharm. 2022;33(4):653-665. doi:10.22146/ijp.3461

Lukić M, Pantelić I, Savić SD. Towards Optimal pH of the Skin and Topical Formulations: From the Current State of the Art to Tailored Products. Cosmetics. 2021;8(3):69. doi:10.3390/cosmetics8030069

Arinjani S, Ariani LW. Pengaruh Variasi Konsentrasi PVA pada Karakteristik Fisik Sediaan Masker Gel Peel-off Ekstrak Daun Ungu (Graptophyllum pictum L. Griff). Media Farm Indones. 2020;14(2):1525-1530.

Rabima R, Marshall M. Uji Stabilitas Formulasi Sediaan Krim Antioksidan Ekstrak Etanol 70% dari Biji Melinjo (Gnetum gnemon L.). Indones Nat Res Pharm J. 2017;2(1):107-121. http://journal.uta45jakarta.ac.id/index.php/INRPJ/article/view/834

Downloads

Published

2023-09-30

How to Cite

Suena, N. M. D. S., Wardani, I. G. A. A. K., & Antari, N. P. U. (2023). Peel Off Mask Formulation of Red Dragon Fruit Extract (Hylocereus lemairei Hook.) and Corn Starch with Variation of Polyvinyl Alcohol (PVA) Concentration. Jurnal Ilmiah Medicamento, 9(2), 127–136. https://doi.org/10.36733/medicamento.v9i2.3576

Issue

Section

Original Articles

Most read articles by the same author(s)

1 2 3 4 5 > >>