Acne Skincare: Formulation of Peel-Off Gel Mask with Ethyl p-Methoxycinnamate from Kaempferia galanga L. using Polyvinyl Alcohol as a Gelling Agent

Authors

  • Ika Maruya Kusuma Institut Sains dan Teknologi Nasional
  • Teti Indrawati Institut Sains dan Teknologi Nasional https://orcid.org/0000-0002-9741-2006
  • Zulfah Zulfah Institut Sains dan Teknologi Nasional

DOI:

https://doi.org/10.36733/medicamento.v11i2.11465

Keywords:

anti-acne peel-off gel mask, ethyl P-Methoxycinnamate, formulation, Kaempferia galanga L.

Abstract

Herbal medicines are increasingly used as antibacterial therapy due to their accessibility and affordability. Kaempferia galanga L. (kencur) rhizome contains ethyl p-methoxycinnamate (EPMS), an active compound with anti-acne properties. EPMS at 1.2% in cream formulations has shown antibacterial activity against Propionibacterium acnes, Staphylococcus epidermidis, and Staphylococcus aureus. However, creams are unsuitable for oily skin as they may worsen acne. Peel-off gels offer a better alternative because it is non-greasy, supports exfoliation, stimulates cell regeneration, minimizes pores, and helps cleanse and moisturize the skin. This study aimed to formulate a physically stable anti-acne peel-off gel containing EPMS using polyvinyl alcohol (PVA) at 10% and 12%. EPMS was isolated from kencur rhizome and incorporated into gel bases. Evaluations included organoleptic properties, viscosity, homogeneity, pH, drying time, spreadability, and accelerated stability at 27 ± 2 °C and 40 ± 2 °C for 21 days. Results showed that EPMS can be successfully formulated into peel-off gels with PVA 10% and 12%. The gels exhibited yellowish-white color, honey-like odor, homogeneity, pH 5.21–5.35, drying time 17–30 minutes, spreadability 55–68 mm, and viscosity 4,900–16,000 cPs. All formulations maintained physical stability under test conditions. This study provides a scientific basis for the development of natural-based cosmetic products that are safe, particularly for oily skin, and do not worsen acne conditions.

Author Biographies

Teti Indrawati, Institut Sains dan Teknologi Nasional

Pharmacy Program, Faculty of Pharmacy

Zulfah Zulfah, Institut Sains dan Teknologi Nasional

Pharmacy Program, Faculty of Pharmacy

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Peel-Off Gel Mask

Submitted

2025-04-20

Accepted

2025-09-16

Published

2025-09-30

How to Cite

Kusuma, I. M., Indrawati, T., & Zulfah, Z. (2025). Acne Skincare: Formulation of Peel-Off Gel Mask with Ethyl p-Methoxycinnamate from Kaempferia galanga L. using Polyvinyl Alcohol as a Gelling Agent. Jurnal Ilmiah Medicamento, 11(2), 193–206. https://doi.org/10.36733/medicamento.v11i2.11465

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