Sun Protection Factor (SPF) Analysis of Jackfruit Leaf Extract (Artocarpus heterophylla Lamk.) Extract 2% with UV-Vis Spectrophotometry
DOI:
https://doi.org/10.36733/medicamento.v10i1.8574Keywords:
Artocarpus heterophylla Lamk.,, Jackfruit Leaf Extract, SPF, UV-protectorAbstract
Ultraviolet light, especially ultraviolet B (UV-B) light, can cause the formation of free radicals, namely reactive oxygen species (ROS). Jackfruit leaves are rich in phenolic compounds such as flavonoids, have good antioxidant properties, and can act as UV-protectors. Several studies using natural materials have been carried out to determine the protective activity of Jackfruit Leaf Extract (Artocarpus heterophylla Lamk.) as a UV-protector based on the Sun Protection Factor (SPF) value. This research was conducted using the in vitro method using spectrophotometry by first macerating the jackfruit leaves, then concentrating them with a rotary evaporator. The extract obtained was formulated into a stick and then dissolved into several concentrations, namely 2,500 ppm, 5,000 ppm, 7,500 ppm, and 10,000 ppm. The results showed that the SPF value at a concentration of 2,500 ppm was 8.09 (maximum protection), at a concentration of 5,000 ppm was 16.83 (ultra protection), at a concentration of 7,500 ppm was 14.34 (maximum protection), and at a concentration of 10,000 ppm (maximum protection). Based on the results of the study, a 2% stick of jackfruit leaf extract (Artocarpus heterophylla Lamk.) had the highest SPF value, namely 16.83 in the ultra-protection category at a concentration of 5,000 ppm, so it has the potential to be a UV-protector.
References
Liliana N, Wiraguna AAGP, Pangkahila W. Krim Ekstrak Panax Ginseng Menghambat Peningkatan Ekspresi MMP-1 dan Penurunan Jumlah Kolagen pada Tikus Wistar Jantan (Rattus norvegicus) yang Dipajan Sinar UV-B. Jurnal e-Biomedik. 2017;5(1):1-7.
Susanti, M., Dachriyanus., Putra D. Aktivitas Perlindungan Sinar UV Kulit Buah Garcinia mangostana Linn Secara In Vitro. Pharmacon. 2012;66(2):37-39.
Bhad PR, Bobde MV, G S. Chemical constituents and biological activities of Artocarpus heterophyllus lam (Jackfruit): A review. International Journal of Clinical Microbiology and Biochemical Technology. 2021;4(1):005-009. doi:10.29328/journal.ijcmbt.1001019
Adrianta KA, Sunadi Putra IMA. Utilization of Artocarpus heterophylla Lamk. As UV Protector In mice exposed to UV-B. Majalah Obat Tradisional. 2018;23(3):112. doi:10.22146/mot.37407
Suena NMDS, Intansari NPOI, Suradnyana IGM, Mendra NNY, Antari NPU. Formulasi dan Evaluasi Mutu Fisik Lip balm dari Ekstrak Kulit Buah Hylocereus lemairei dengan Variasi Konsentrasi Cera Alba. Usadha. 2022;2(1):65-72. doi:10.36733/usadha.v2i1.5583
Suena NMDS, Wardani IGAAK, Antari NPU. Formulasi Masker Peel Off Ekstrak Buah Naga Merah (Hylocereus lemairei Hook.) dan Pati Jagung dengan Variasi Konsentrasi Polyvinyl Alcohol (PVA). Jurnal Ilmiah Medicamento. 2023;9(2):127-136. doi:10.36733/medicamento.v9i2.3576
Suena NMDS, Ariani NLWM, Antari NPU. Physical Evaluation and Hedonic Test of Sandalwood Oil (Santalum album L.) Cream as an Anti-Inflammatory. Jurnal Ilmiah Medicamento. 2022;8(1):22-30. doi:10.36733/medicamento.v8i1.3425
Dutra EA, Oliveira DAG da C, Kedor-Hackmann ERM, Santoro MIRM. Determination of sun protection factor (SPF) of sunscreens by ultraviolet spectrophotometry. Revista Brasileira de Ciências Farmacêuticas. 2004;40(3):381-385. doi:10.1590/S1516-93322004000300014
Damogalad V, Edy HJ, Supriati HS. Formulasi Krim Tabir Surya Ekstrak Kulit Nanas (Ananas comosus L Merr) dan Uji in Vitro Nilai Sun Protecting Factor (SPF). PHARMACON Jurnal Ilmiah Farmasi – UNSRAT. 2013;2(02):39-43. https://ejournal.unsrat.ac.id/v3/index.php/pharmacon/article/view/1577
Nur S, Sami FJ, Awaluddin A, Afsari MIA. Korelasi Antara Kadar Total Flavonoid dan Fenolik dari Ekstrak dan Fraksi Daun Jati Putih (Gmelina Arborea Roxb.) Terhadap Aktivitas Antioksidan. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal). 2019;5(1):33-42. doi:10.22487/j24428744.2019.v5.i1.12034
Gunawan I. Perbandingan pH dan Daya Sebar Krim Ekstrak Kulit Nanas (Ananas comosus (L). Merr). Jurnal Analis Kesehatan. 2018;7(1):680. doi:10.26630/jak.v7i1.918
Geoffrey K, Mwangi AN, Maru SM. Sunscreen products: Rationale for use, formulation development and regulatory considerations. Saudi Pharmaceutical Journal. 2019;27(7):1009-1018. doi:10.1016/j.jsps.2019.08.003
Notario D, Aditya M, Rollando R, Prilianti KR. Analisis Faktor Perlindungan Matahari (FPM) dari Sediaan Tabir Surya secara Spektrofotometri dengan Metode Kuadrat Terkecil Sebagian Jack-Knife. Natural Science: Journal of Science and Technology. 2017;6(1):1-10. doi:10.22487/25411969.2017.v6.i1.8072
Putra IGNAWW, Arimbawa PE, Artini NPR. Potential of Frangipani (Plumeria alba) Leaves Extract as Ultra Violet Protection. Borneo Journal of Pharmacy. 2020;3(4):257-261. doi:10.33084/bjop.v3i4.1644
Rahmawanty D, Zakiah Z, Fadhillaturahman F. Uji Potensi sebagai Tabir Surya secara in Vitro Fraksi Etil Asetat Kulit Batang Tanaman Bangkal (Nauclea subdita). Prosiding Seminar Nasional dan Workshop: Perkembangan Terkini Sains Farmasi dan Klinik 5. 2015;(November):6-7.
Rusita YD, A.S I. Aktifitas Tabir Surya Dengan Nilai Sun Protection Factor (SPF) Sediaan Losion Kombinasi Ekstrak Kayu Manis Dan Ekstrak Kulit Delima Pada Paparan Sinar Matahari Dan Ruang Tertutup. Jurnal Kebidanan dan Kesehatan Tradisional. 2017;2(1). doi:10.37341/jkkt.v2i1.26
Devi M, Sunaryo N, Mansoor A. Antioxidant analysis of Artocarpus heterophyllus drink. IOP Conference Series: Earth and Environmental Science. 2021;733(1):012087. doi:10.1088/1755-1315/733/1/012087
Shovyana HH, Zulkarnain AK. Physical Stability and Activity of Cream W/O Ethanolic Fruit Extract Mahkota Dewa (PHaleria macrocarph (Scheff.) Boerl.) as a Sunscreen. Traditional Medicine Journal. 2013;18(2):109-117.
He H, Li A, Li S, Tang J, Li L, Xiong L. Natural components in sunscreens: Topical formulations with sun protection factor (SPF). Biomedicine & Pharmacotherapy. 2021;134(December 2020):111161. doi:10.1016/j.biopha.2020.111161
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Jurnal Ilmiah Medicamento
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The copyright holder for the work is the Jurnal Ilmiah Medicamento.
Jurnal Ilmiah Medicamento is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format
- The licensor cannot revoke these freedoms if you follow the license terms.
Under the following terms:
-
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so reasonably but not in any way that suggests the licensor endorses you or your use.
-
NonCommercial — You may not use the material for commercial purposes.
-
NoDerivatives — If you remix, transform, or build upon the material, you may not distribute the modified material.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.