Antiradical Activity Study of Momordica charantia L Seeds Based on DPPH and its Secondary Metabolites Analysis

Baiq Desy Ratnasari; Diah Miftahul Aini; Imam Syahputra Yamin; Gladeva Yugi Antari

doi:10.36733/medicamento.v8i1.3352

Authors

Baiq Desy Ratnasari STIKES Kusuma Bangsa
Diah Miftahul Aini STIKES Kusuma Bangsa
Imam Syahputra Yamin STIKES Kusuma Bangsa
Gladeva Yugi Antari STIKES Griya Husada Sumbawa

DOI:

https://doi.org/10.36733/medicamento.v8i1.3352

Keywords:

antioxidant, bitter melon seeds, chemical compound, GC-MS

Abstract

Momordica charantia L seed is classified as the domestic waste even though it has many health benefits, namely as anti-tumor, anti-virus, and as a medicine to increase the body resistance. Therefore, this study was designed to examine the antioxidant activity of the ethanol extract of the seeds using the DPPH method. Furthermore, a GC-MS analysis will be carried out to determine the chemical compounds that play a role in the bioactivity. Based on the absorbance of DPPH in three repetitions, the average value of DPPH inhibition by 95% ethanol extract of bitter melon seeds was 60.45%, in which classified as a good radical absorbance. The GC-MS results showed that the ethanol extract of bitter melon seeds contained ten chemical compounds consisting of sesquiterpenes, fatty acids, and alkanes, which affecting the radical absorbance of M. charantia extract.

Author Biographies

Baiq Desy Ratnasari, STIKES Kusuma Bangsa

Pharmacy Bachelor Program

Diah Miftahul Aini, STIKES Kusuma Bangsa

Pharmacy Bachelor Program

Imam Syahputra Yamin, STIKES Kusuma Bangsa

Hospital Administration Undergraduate Study Program

Gladeva Yugi Antari, STIKES Griya Husada Sumbawa

Midwifery Diploma Three Study Program

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