A Retrospective Study of Drug Used and Potential Drug Interactions in Patients with Systemic Lupus Erythematosus

Siluh Putu Astini; Ni Nyoman Wahyu Udayani; Herleeyana Meriyani

doi:10.36733/medicamento.v7i2.2271

Authors

Siluh Putu Astini Universitas Mahasaraswati Denpasar
Ni Nyoman Wahyu Udayani Universitas Mahasaraswati Denpasar
Herleeyana Meriyani Universitas Mahasaraswati Denpasar

DOI:

https://doi.org/10.36733/medicamento.v7i2.2271

Keywords:

penggunaan obat, potensi interaksi obat, SLE

Abstract

Systemic Lupus Erythematosus is a complex autoimmune disease involving multiple organs with various clinical manifestations and prognoses. The complexity of treatment and the emergence of drug-related problems demands a greater role of pharmacy in conducting pharmaceutical care. The aim of this study was to explore drug use and to identify potential drug interactions in SLE outpatients at one hospital in Denpasar. This study was a retrospective and observational study collection. The study used secondary data in medical records during January-December 2019. There were 210 SLE people consisting of 12.86% males and 87.14% women. 29.05% of the patients were aged 17-25 years. The most immunosuppressants used were methylprednisolone (48.93%), the most analgetic used was acetaminophen (88.46%). 12.10% of patients had a potentially serious drug interaction, 80.40% had a moderate and 7.5% had minor drug interaction.

Author Biographies

Siluh Putu Astini, Universitas Mahasaraswati Denpasar

Fakultas Farmasi

Ni Nyoman Wahyu Udayani, Universitas Mahasaraswati Denpasar

Fakultas Farmasi

Herleeyana Meriyani, Universitas Mahasaraswati Denpasar

Departemen Farmakologi dan Farmasi Klinik
Program Studi Sarjana Farmasi
Fakultas Farmasi

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