Pattern of Antipsychotics in Schizophrenia Outpatients at Lampung Province Mental Hospital

Isnenia Isnenia

doi:10.36733/medicamento.v8i1.3201

Penulis

Isnenia Isnenia Politeknik Kesehatan Tanjungkarang

DOI:

https://doi.org/10.36733/medicamento.v8i1.3201

Kata Kunci:

antipsikotik kombinasi, pasien rawat jalan, Schizophrenia

Abstrak

Skizofrenia sebagai gangguan jiwa kronis mengalami peningkatan jumlah dalam tiga dekade terakhir DALYs (Disability Adjusted Life Years). Antipsikotik telah menjadi andalan pengobatan. Penggunaan kombinasi zat aktif antipsikotik tipikal/atipikal sangat sering dilakukan. Tujuan dari penelitian ini adalah untuk melihat karakteristik pasien dan karakteristik klinis termasuk jumlah dan jenis kombinasi antipsikotik. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kuantitatif dan cross sectional. Data umur, jenis kelamin, lama sakit, status pembiayaan, jumlah obat, dan nama antipsikotik yang digunakan diambil dari rekam medis dan lembar resep dari 207 pasien rawat jalan yang didiagnosis skizofrenia. Data tersebut kemudian diolah dan dianalisis menggunakan analisis univariat. Pasien skizofrenia rawat jalan didominasi laki-laki 62,8%, usia 26-35 tahun 32,4%, lama sakit lebih dari 12 bulan 92,3%, menggunakan asuransi kesehatan 82,8%, rata-rata jumlah obat yang diresepkan 3,5 obat. Kombinasi dengan dua antipsikotik adalah 58%. Kombinasi atipikal-tipikal (30,9%) lebih tinggi dengan kebanyakan risperidone-clozapine. Kombinasi tipikal-tipikal (19,3%) termasuk klorpromazin-haloperidol, trifluoperazin-klorpromazin. Kombinasi atipikal-atipikal termasuk risperidon-clozapine. Kombinasi ketiga antipsikotik mencapai 7,7%. Kesimpulan penelitian ini menunjukkan bahwa kombinasi antipsikotik banyak digunakan dalam pengobatan skizofrenia, dengan dua jenis antipsikotik yang paling banyak digunakan. Kombinasi risperidone-klorpromazin adalah yang paling umum yaitu 21,7%.

Biografi Penulis

Isnenia Isnenia, Politeknik Kesehatan Tanjungkarang

Diploma Tiga Farmasi, Politeknik Kesehatan Tanjungkarang

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