Uji Efektivitas Antibakteri Ekstrak Etanol 96% Tanaman Gonda (Sphenoclea zeylanica Gaertn) terhadap Staphylococcus aureus

Pande I Ketut Sukadiasa; Ni Putu Wintariani; I Gusti Ngurah Agung Windra Wartana Putra

doi:10.36733/medicamento.v9i1.4644

Authors

Pande I Ketut Sukadiasa Universitas Bali Internasional
Ni Putu Wintariani Universitas Bali Internasional
I Gusti Ngurah Agung Windra Wartana Putra Universitas Bali Internasional

DOI:

https://doi.org/10.36733/medicamento.v9i1.4644

Keywords:

antibacterial, ethanol 96% extract, Sphenoclea zeylanica Gaertner, Staphylococcus aureus

Abstract

Staphylococcus aureus is a gram-positive bacterium that is the leading cause of infections of the skin, soft tissue, respiratory tract, bones, and joints. The use of traditional medicine is generally considered safer than the use of modern medicine. One of the plants in Indonesia that can be used as medicine is the Gonda plant (Sphenoclea zeylanica Gaertn). The phytochemical compounds in the gonda plant are saponins, flavonoids, phenols, alkaloids, and steroids, which have antibacterial activity. This study aims to determine the content of secondary metabolites and the antibacterial activity of 96% ethanol extract of Gonda plants with different concentration variations against Staphylococcus aureus bacteria. This research is quantitative research with an experimental research design. The results showed that the 96% ethanol extract of the gonda plant contained flavonoids, saponins, tannins, steroids, and alkaloids and showed antibacterial activity. The average inhibition zone concentration of the extract was 5%, 10%, 15%, and 20%, respectively, 9.4 ± 0.19 mm, 12.56 ± 0.18 mm, 14.63 ± 0.30 mm, 17.45 ± 0.36 mm in the medium to strong category. There was a significant difference (P<0.05) between the inhibition zone values of each concentration, where the increase in the inhibition zone value was directly proportional to the increase in the extract concentration. The extract with a concentration of 20% had an immense inhibition zone value of 17.45 mm.

Author Biographies

Pande I Ketut Sukadiasa, Universitas Bali Internasional

Clinical Pharmacy Study Program, Faculty of Health Sciences

Ni Putu Wintariani, Universitas Bali Internasional

Clinical Pharmacy Study Program, Faculty of Health Sciences

I Gusti Ngurah Agung Windra Wartana Putra, Universitas Bali Internasional

Clinical Pharmacy Study Program, Faculty of Health Sciences

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