TREATMENT OF HERPES ASSOCIATED ERYTHEMA MULTIFORME (HAEM)

TATALAKSANA HERPES ASSOCIATED ERYTHEMA MULTIFORME (HAEM)

Authors

  • Raziv Ganesha FKG Universitas Mahasaraswati
  • Rina Kartika Sari Universitas Islam Sultan Agung

DOI:

https://doi.org/10.46862/interdental.v19i1.6350

Keywords:

Erithema Multiforme, HSV-1 , Management of Herpes Associated Erythema Multiforme

Abstract

Introduction: Herpes Associated Erythema Multiforme (HAEM) is Erythema multiforme (EM) caused herpes virus infection.  EM a caused by an acute hypersensitivity reaction that occurs in the mucocutaneous area. HAEM is hypersensitivity reaction that occurs due to a hypersensitivity reaction to the herpes virus. Case: 17 year old male complaints of itching and dry on his lips since 5 days ago. patient said that ± 7 days ago he had a fever which lasted for 2 days then after the fever went down his lips felt itchy and dry. On clinical examination, desquamation with yellowish brown crusts was found on the vermilion of the upper and lower lips. Case Treatment: patient is given Aloclair® Gel and Becomzet®. Patient is referred for a complete blood count, Total IgE and IgM and IgG HSV-1 antibody testing. The patient was then given hydrocortisone cream 2.5% used 3 times a day. The patient recovered 10 days after the first visit. Discussion: HAEM is triggered by an immunological response in which an immune complex reaction occurs as a result of an immune response to certain antigens such as the herpes simplex virus or certain types of drugs. In cases of HAEM the herpes virus that triggers it is usually HSV-1 & HSV-2. Diagnosis is confirmed by Total IgE and HSV-1 Antibody Tests. Conclucion: Management of cases of HAEM can be successfully determined by establishing the correct diagnosis which requires investigations so that we can rule out the differential diagnosis and provide appropriate treatment

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References

Osterne, RLV, Brito, RGM, Pacheco, IA, Alves, APN, Sousa, FB. Management of Erythema Multiforme (EM) Associated with Recurrent Herpes Infection. A Case Report. J.C.D 2009; (75)8: 597-601.

Kishore, Sunil R Panat, Ashish Aggarwal, Nitin Upadhyay NA. Herpes Associated Erythema Multiforme-A Diagnostic Dilemma Mallika. International Journal of Scientific Study 2013; 1(02): 1-6

Chen Y-C, Chang C-H. Herpes Simplex Virus -Associated Recurrent Erythema Multiforme: The Implication of MHC Class Molecules on Susceptibility. Dermatol Sin. 2008; 165–70.

Regezi, JA, Sciubba, JJ, Jordan, RCK. Oral Pathology Clinical Pathology Correlation Seventh Edition. NewYork: Elsevier; 2017.

Glick M. Burket's Oral Medicine. 12th ed. Connecticut (USA): People's Medical Publishing House; 2015. p. 104-110.

Laskaris, George. Pocket Atlas of Oral Disease 3nd edition. New York: Thieme; 2020.

Marlina E, Soenartyo H. Prymary Herpetic Gingivostomatitis pada individu dewasa muda, Dentofasial 2012; (11)2: 111 -114.

Fatahzadeh M, Schwartz AR. Human herpes simplex virus infection: epidemiology, pathogenesis, symptomatology, diagnosis and management. J Am Acad Dermatol 2007; 17: 5.

KEMENKES. Pedoman Intepretasi Data Klinik. Jakarta. 2011.

Baratawidjaja, KG.. Imunologi Dasar. Jakarta: Balai penerbit FKUI; 2000.

Samaranayake, L. Essential Microbiology for Dentistry 4th Ed. Alison Taylor, ed., Edinburg: Churchill Livingstone Elseiver Ltd; 2012.

Sahraei, Z, Mirabzadeh, M, Eshragi, A. Erythema Multiforme Associated with Misoprostol: A Case Report. Am J Ther. 2016; 23(5): 2–5.

Guilliams, Thomas G, Edward, L. Chronic Stress and the HPA axix: Clinical Assesment and Therapeutic Considerations. A review of Natural & Nutraceutical Therapies for Clinical Practice 2010 (9)2: 1-11.

Noisakran S, Hallford W, Veress L. Role of the Hypothalamic Pituitary Adrenal Axis and IL-6 in Stress-Induced Reactivation of Latent Herpes simplex Virus Type-1. The American Journal of Immunologists1998; (160)11: 5441-5447.

Gürkan A, Sarikaya E, Demirkesen C, Yilmaz G, Midilli K. The Overlap of Fixed Drug Eruption and Human Herpes Virus Type II Associated Erythema Multiforme. J Turk Acad Dermatol. 2007; 1(1): 3.

Sen P, Chua SH. A case of recurrent erythema multiforme and its therapeutic complications. Ann Acad Med Singapore. 2004; 33(6): 793–6.

Blyta Y, Kocinaj A., Ferizi M., Gerqari A & Ahmeti N. Multiforme Erythema, In Child, After Repeated Herpes Simplex Infections– Case Presentation. J Clin Exp Dermatology 2011; (2)5.

Kalbemed A. Aloclair Plus [Internet]. Kalbemed.com. 2013 [cited 7 April 2016]. Available from: http://www.kalbemed.com

Ritter JM, Lewis LD, Mant TG, Ferro L. A Textbook of Clinical Pharmacology and Therapeutics (5th ed). London: Hodder Arnold, 338 Euston Road. 2008; p. 413-414.

Setyabudi, R., Nafrialdy, I. Farmakologi dan Terapi. Ed 6. Jakarta: FKUI; 2016. p. 283,505

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Published

2023-06-23

How to Cite

1.
Ganesha R, Kartika Sari R. TREATMENT OF HERPES ASSOCIATED ERYTHEMA MULTIFORME (HAEM): TATALAKSANA HERPES ASSOCIATED ERYTHEMA MULTIFORME (HAEM). interdental [Internet]. 2023 Jun. 23 [cited 2024 May 3];19(1):11-6. Available from: https://e-journal.unmas.ac.id/index.php/interdental/article/view/6350