Validation of Analytical Methods of Several Secondary Metabolic Compounds in Andrographis paniculata, Zingiber officinale var. rubrum, and Nigella sativa as COVID-19 Therapy: A Review

Farendina Suarantika; Nabila Hadiah Akbar

doi:10.36733/medicamento.v8i1.3355

Penulis

Farendina Suarantika Universitas Islam Bandung
Nabila Hadiah Akbar Politeknik Unggulan Kalimantan

DOI:

https://doi.org/10.36733/medicamento.v8i1.3355

Kata Kunci:

andrografolid, COVID-19, gingerol, timokuinon

Abstrak

Beberapa tanaman Indonesia mengandung senyawa aktif yang dapat membatasi infeksi dan replikasi SAR-CoV-2 berdasarkan aktivitasnya terhadap target terapeutik yang relevan. Kajian pustaka ini bertujuan untuk meninjau metode analisis tervalidasi pada tanaman sambiloto (Andrographis paniculata), jahe merah (Zingiber officinale var. rubrum), dan jintan hitam (Nigella sativa), yang berpotensi memiliki aktivitas terapeutik terhadap SARS-CoV-2. Sumber informasi yang digunakan pada kajian pustaka ini diperoleh dengan menggunakan search engine seperti Science direct, Google Scholar, dan PubMed. Andrografolid (sambiloto), gingerol (jahe merah), dan timokuinon (jintan hitam) terbukti secara spesifik mampu menginaktivasi SARS-CoV-2 dengan akurasi target yang baik. Metode analisis tanaman yang tervalidasi secara umum menggunakan RP-HPLC/HPTLC, Spektrofotometri UV-Vis, GC-FID, GC, dan UHPLC-DAD.

Biografi Penulis

Farendina Suarantika, Universitas Islam Bandung

Program Studi Farmasi, Fakultas MIPA

Nabila Hadiah Akbar, Politeknik Unggulan Kalimantan

Program Studi Diploma Tiga Farmasi

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