THE EFFECTIVENESS OF PROBIOTIC LOZENGES LACTOBACILLUS REUTERI PRODENTIS IN INCREASING SALIVARY SECRETION
Efektivitas Tablet Hisap Probiotik Lactobacillus Reuteri Prodentis Terhadap Sekresi Saliva
DOI:
https://doi.org/10.46862/interdental.v18i2.5468Keywords:
Lactobacillus Reuteri Prodentis, saliva secretion, periodontal diseaseAbstract
Introduction: Indonesian people experience dental and oral health problems
as much as 57.6%, one of the dental and oral health problems that is often
treated is periodontal disease. Alternative prevention of periodontal disease is
by consuming probiotics (Lactobacillus reuteri). Probiotic (Lactobacillus
reuteri) contains L. reuteri bacteria which inhibits periodontal and cariogenic
pathogenic bacteria so that it is suspected to increase salivary flow rate. Objectives: to determine the effectiveness of probiotics (Lactobacillus reuteri) to increase salivary secretion. Materials and methods: this study
used an experimental approach with a pre-test and post-test design. The research subjects were 30 students of the Faculty of Dentistry, Mahasaraswati
Denpasar University who met the research criteria. The sample was divided
into two groups, namely the group that consumed the probiotic Interlac Pro-D lozenges and the group that consumed a placebo. The data taken were
the salivary flow rate, which was measured twice, before and after administration of the probiotic Interlac Pro-D lozenges and placebo. Data
analysis: data is processed using paired t-test and independent t-test. Results
and Discussion: The results showed that the average salivary secretion
before consuming Interlac Pro-D probiotic tablets was 0.3073 ± 0.02492 ml/
minute, increasing to 0.328 ± 0.03299 ml/minute, placebo increasing to 0.276
± 0.02293 ml/minute to 0.2853 ± 0.0256 ml/minute. There was a difference
in the effectiveness of increasing salivary secretion between the groups consuming the probiotic Interlac Pro-D tablets and placebo (p <0.005).
Conclusion: taking probiotic lozenges Interlac Pro-D (Lactobacillus reuteri
prodentis) is effective in increasing salivary secretion which is beneficial for
preventive therapy of periodontal disease.
Downloads
References
Larasati, R. (2012). ‘Hubungan kebersihan mulut dengan penyakit sistemik dan usia harapan hidup’, Jurnal Skala Husada 9(1), 97-104.
Diah, Widodorini, T. & Nugraheni, N.E. (2018)> ‘Perbedaan angka kejadian gingivitis antara usia pra-pubertas dan pubertas di Kota Malang’, E-Prodenta Journal of Dentistry 2(1), 108-115.
Fitria, K. T (2018). ‘Hubungan Polimorfisme Gen Reseptor Vitamin D FOK I Dengan Periodontitis Kronis’, tesis, Medan.
Hopcraft MS, Tan C (2010). Xerostomia: an update for clinicians. Aust Dent J. ;55(3):238-44.
Adzakiyah, T., Lipoeto, I., & Kasuma, N. (2015). Pengaruh Berkumur dengan Larutan Ekstrak Siwak (Salvadora persica) Terhadap pH Saliva Rongga Mulut. Jurnal Sains Farmasi & Klinis, 2(1), 74-77.
Suryadinata, A. (2012). Kadar Bikarbonat Penderita Karies dan Bebas Karies. Sainstis; 1 (1): 35-42.
Shetty, C., Hegde, M.N., Devadiga, D. 2013. Correlation Between Dental Caries With Salivary Flow, pH, and Buffering Capacity in Adult South Indian Population: An In-Vitro Study. Int. J. Res. Ayurveda Pharm; 4 (2): 219-223.
Kaur, M., Shah, S. 2012. A Study of Analytical Indicators of Saliva. Annals and Essences of Dentistry; IV:9-18.
Walsh, L.J. 2007. Clinical Aspects of Salivary Biology for the Dental Clinician. International Dentistry South Africa (Australasian Edition); 2 (3): 16-20.
Macpherson, P. 2013. The Role of Saliva in Oral Health and Disease.
Surja, J., & Soetopo, M. S. (2017). Peran Probiotik dalam Menurunkan Kejadian Gingivitis pada Anak dengan Leukemia Limfositik Akut. Paper presented at Pertemuan Ilmiah Nasional Ilmy Kedokteran Gigi Anak ke-10, Jakarta, Indonesia.
Pradeep K, Kuttappa MA, Prasana KR SADJ (2014). Probiotics and oral health: an update; 69(1):20-4.
Lumikari, M.L., Loimaranta,V. 2000. Saliva and Dental Caries. Adv Dent Res; 14: 40-47.
Hatakka K, Ahola AJ, Yli-Knuuttila H, Richardson M, Poussa T, Meurman JH, Korpela R J Dent Res (2007). Probiotics reduce the prevalence of oral candida in the elderly--a randomized controlled trial. 86(2):125-30.
Adzakiyah, T., Lipoeto, I., & Kasuma, N. (2015). Pengaruh Berkumur dengan Larutan Ekstrak Siwak (Salvadora persica) Terhadap pH Saliva Rongga Mulut. Jurnal Sains Farmasi & Klinis, 2(1), 74-77.
Rantonen, P. (2003). “Salivary Flow and Komposition in Healthy and Diseased Adults” (dissertation). Finland: Helsinki University.
Saluja, P., Shetty, V., Dave, A., Arora, M., Hans, V. and Madan, A., (2014). Comparative evaluation of the effect of menstruation, pregnancy and menopause on salivary flow rate, pH and gustatory function. Journal of clinical and diagnostic research: JCDR, 8(10), p.ZC81.
Mack DR, Ahrne S, Hyde L, Wei S, Hollingsworth MA (2003). Extracellular MUC3 mucin secretion follows adherence of Lactobacillus strains to intestinal epithelial cells in vitro. Gut 52:827-833
Madukwe, I. U., 2014, Anatomy of the periodontium: A biological basis for radiographic evaluation of periradicular pathology, Journal of Dentistry and Oral Hygiene, 6(7), 70-76.
Mu Q, Tavella VJ, Luo XM. Role of Lactobacillus reuteri in human health and diseases. Frontiers in microbiology. 2018 Apr 19;9:757.
Downloads
Published
How to Cite
Issue
Section
License
- Every manuscript submitted to must observe the policy and terms set by the Interdental Jurnal Kedokteran Gigi (IJKG)
- Publication rights to manuscript content published by the Interdental Jurnal Kedokteran Gigi (IJKG) is owned by the journal with the consent and approval of the author(s) concerned.
- Full texts of electronically published manuscripts can be accessed free of charge and used according to the license shown below.