Jurnal Ilmiah Medicamento
https://e-journal.unmas.ac.id/index.php/Medicamento
<p><a title="Profil Sinta JINTO" href="https://sinta.kemdikbud.go.id/journals/profile/7980" target="_blank" rel="noopener"><strong>Jurnal Ilmiah Medicamento</strong></a> abbreviated as <em>JINTO</em>, with the registered e-ISSN <a title="e-ISSN Jurnal Ilmiah Medicamento" href="https://issn.brin.go.id/terbit/detail/1409274190" target="_blank" rel="noopener">2356-4814</a>, is an <strong>open-access</strong> scientific journal in the field of pharmacy. Each and every manuscript in this journal is reviewed by two reviewers and conducted through a <em><strong>double-blind peer review</strong></em> system to ensure objectivity and high quality assessment. JINTO has been accredited by ARJUNA with a <a href="https://drive.google.com/file/d/1Vd3DsOLOw5PUVxJOtpRo5NYBkbhcef5G/view?usp=sharing" target="_blank" rel="noopener"><strong>SINTA 4</strong></a> ranking from Vol.5 No.1 in 2019 until Vol.9 No.2 in 2023. Starting from Vol.9 No.1 in 2023, the journal has been elevated to a <a href="https://drive.google.com/file/d/1jk-jJuFhmSvbfim1lPX5-HUY7J-hIux4/view?usp=sharing" target="_blank" rel="noopener"><strong>SINTA 2</strong></a> accreditation, as per the Decree of the Director General of Higher Education, Research, and Technology, Ministry of Education, Culture, Research, and Technology of the Republic of Indonesia, Number <a href="https://drive.google.com/file/d/1jk-jJuFhmSvbfim1lPX5-HUY7J-hIux4/view?usp=sharing" target="_blank" rel="noopener">177/E/KPT/2024</a>, dated October 15, 2024.</p> <p>Initially published by the Akademi Farmasi Saraswati Denpasar, the journal transitioned to being published by the <a title="Fakultas Farmasi Universitas Mahasaraswati Denpasar" href="http://farmasi.unmas.ac.id/" target="_blank" rel="noopener"><strong>Faculty of Pharmacy, Universitas Mahasaraswati Denpasar</strong>,</a> in early 2019 following the integration of the academy into the university as its Faculty of Pharmacy.</p> <p>JINTO is published biannually in <strong>March</strong> and <strong>September</strong> and aims to disseminate current scientific knowledge to researchers in the pharmacy field. The journal accepts original research articles and review articles encompassing <strong>various areas of pharmaceutical science</strong>, including <em>Pharmacology and Toxicology</em>; <em>Clinical and Community Pharmacy</em>; <em>Pharmaceutical Chemistry and Analysis</em>; <em>Pharmaceutical Biology and Natural Products</em>; <em>Pharmaceutical Technology</em>; <em>Pharmaceutical Microbiology and Biotechnology</em>; <em>Regulatory Affairs and Pharmacy Marketing Research</em>; and <em>Alternative medicine</em>.</p>Fakultas Farmasi Universitas Mahasaraswati Denpasaren-USJurnal Ilmiah Medicamento2356-4814Analytical Methods for Revealing the Composition of Fruit Flavor E-Cigarette E-Liquid: A Review
https://e-journal.unmas.ac.id/index.php/Medicamento/article/view/11099
<p>The use of e-cigarettes is increasing, one of which is due to fruit-flavored e-liquids. The chemical compounds that make up these flavors play a role in providing flavor characteristics, but if inhaled, they can potentially negatively affect health. Understanding what chemical compounds are found in e-liquid flavors is very important to determine the toxicity effects of e-cigarettes. This article aimed to review the analytical methods that had been carried out by previous studies in identifying e-liquid flavor compounds. Literature was collected through searches in reputable scientific databases, including ScienceDirect, Scopus, Web of Science, PubMed, and Google Scholar, using relevant keywords. From the initial search, 35 relevant articles were found and then selected based on inclusion and exclusion criteria, resulting in 10 articles for further analysis. The selected literature consisted of research focusing on chromatographic methods, specifically Gas Chromatography (GC) and Liquid Chromatography (LC). Further developments, such as the combination of GC with Mass Spectrometry (MS) and Ion Mobility Spectrometry (IMS), as well as LC with MS/MS and Electrospray Ionization (ESI), were shown to improve the sensitivity and selectivity of the analysis. These findings emphasize the importance of choosing the right analytical method for the compounds to be identified. The results also discuss the advantages and challenges, which can guide in choosing the right analytical method to promote the development of better safety standards.</p>Aghnia NabilaMochammad YuwonoMochammad Taha Ma'rufShalsa Septia Zulni
Copyright (c) 2025 Aghnia Nabila, Mochammad Yuwono, Mochammad Taha Ma'ruf, Shalsa Septia Zulni
https://creativecommons.org/licenses/by-nc-nd/4.0
2025-03-232025-03-23111142410.36733/medicamento.v11i1.11099The Nature of Opioids Used as Pain Management in A Public Hospital in Bali
https://e-journal.unmas.ac.id/index.php/Medicamento/article/view/10105
<p>Opioids are the mainstay of pain management, particularly in chronic pain-related and nonrelated cancer. Studies have shown that the number of opioids used globally varies. It was used excessively in some parts, while in others, it was underused. Little study is known on how opioids are used in Indonesia. This study aimed to identify indications of opioids prescribed and types of opioids used, as well as assess the nature of opioid therapy as pain management for chronic and non-related cancer. This retrospective study was conducted in a public hospital in Bali, Indonesia. Data was collected from all inpatients who received opioids in the hospital from 2018 to 2020. Patients’ age, gender, as well as opioid information such as types of opioids and used for treatment for cancer or non-cancer patients, were pooled and analyzed descriptively. This study found that fentanyl injection was the most opioid prescribed by anesthesiologists as preoperative medications. Opioids were prescribed mostly for non-cancer patients, and limited opioids were prescribed for cancer patients. Future research is required to evaluate factors that influence opioid prescriptions in hospitals.</p>Desak Ketut ErnawatiAgata Widatama
Copyright (c) 2025 Desak Ketut Ernawati, Agata Widatama
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2025-03-232025-03-231111610.36733/medicamento.v11i1.10105Carrageenan from Balinese Red Seaweed (Gracilaria sp). as Antibacterial against Eight Pathogenic Bacteria
https://e-journal.unmas.ac.id/index.php/Medicamento/article/view/10349
<p>The increase in infection cases every year, coupled with the rise in resistance cases, increases the urgency of exploring antimicrobial agents. <em>Gracilaria</em> sp. is a red seaweed that is widely known as one of the potential producers of active metabolites, sulfated polysaccharides. Carrageenan is one form of sulfated polysaccharide that has antimicrobial activity. This study was conducted to evaluate the antibacterial activity of carrageenan derived from <em>Gracilaria</em> sp. against several pathogenic bacteria, including <em>Escherichia coli, Staphylococcus aureus</em>, <em>Staphylococcus epidermidis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, Streptococcus pyogenes</em>, and <em>Salmonella typhi</em>. Carrageenan was extracted from Gracilaria sp. samples obtained from the South Denpasar area (Bali) using KOH. An antibacterial activity assay of carrageenan was carried out using an agar well diffusion method with nutrient agar media. Tests were conducted at concentrations of 1 and 5 mg/mL (<em>E. coli </em>and <em>S. epidermidis</em>), 20, 30, 40 mg/mL (<em>S. aureus, S. pyrogenes, E. faecalis, </em>and<em> S. typhi</em>), 50, 75, and 100 mg/mL (<em>P. aeruginosa </em>and<em> K. pneumoniae</em>). Incubation was carried out for 24 hours at ± 37 °C. Data were analyzed statistically by one-way ANOVA and Kruskal-Wallis with a 95% confidence level. The results showed that carrageenan extracted from <em>Gracilaria</em> sp. exhibited significant antibacterial activity against several pathogenic bacteria, especially gram-negative bacteria. The antibacterial activity produced in this study was proportional to the increase in concentration, where the inhibitory activity produced increased as the concentration of carrageenan increased. It can be concluded that carrageenan has the potential to be an antibacterial.</p>Maria Malida Vernandes SasadaraErna CahyaningsihNi Luh Kade Arman Anita DewiPutu Era Sandhi Kusuma YudaI Gusti Agung Ayu Kusuma WardaniDebby JuliadiNi Kadek Dila Pratiwi PutriNi Kadek Nisa Leoni PutriI Wayan Agus DarmawanNi Kadek Pradnya Yanti
Copyright (c) 2025 Maria Malida Vernandes Sasadara, Erna Cahyaningsih, Ni Luh Kade Arman Anita Dewi, Putu Era Sandhi Kusuma Yuda, I Gusti Agung Ayu Kusuma Wardani, Debby Juliadi, Ni Kadek Dila Pratiwi Putri, Ni Kadek Nisa Leoni Putri, I Wayan Agus Darmawan, Ni Kadek Pradnya Yanti
https://creativecommons.org/licenses/by-nc-nd/4.0
2025-03-232025-03-2311161310.36733/medicamento.v11i1.10349