EFEKTIVITAS DAYA HAMBAT EKSTRAK DAUN BIDARA ARAB (ZIZIPHUS SPINA-CHRIST) TERHADAP BAKTERI STAPHYLOCOCCUS AUREUS SECARA IN VITRO
Kata Kunci:
Arabian bidara leaves, the inhibition, Staphylococcus aureusAbstrak
Instroduction: Staphylococcus aureus is one of the normal microflora in the oral cavity. However, in certain circumstances, these bacteria can turn into pathogens due to predisposing factors, such as poor oral hygiene. Some oral diseases caused by Staphylococcus aureus are abscess, gingivitis, angular cheilitis, parotitis, staphylococcal mucositis, and denture stomatitis. An alternative material that can be used as an inhibitor for the growth of this bacteria is the leaves of the Arabian bidara (Ziziphus spina-christi L.). This is because the leaves of the Arabian bidara contain flavonoids, alkaloids, saponins, tannins, and steroids. This study aimed to determine the effect of the concentration of bidara Arabic leaf extract on the inhibition of the growth of Staphylococcus aureus bacteria.
Methods: The extraction method was maceration with ethanol 96% as the solvent. This study used a modification of the Kirby-Bauer method.
Result: The result showed that the diameter of the inhibition zone of bidara Arabic leaf extract at concentrations of 20%, 30%, and 40% was 10.0 mm; 10800±0.27mm; and 12.20±0.45 mm. It means the higher the concentration of bidara Arabic leaf extract, the higher the inhibitory or antibacterial power that is formed.
Conclusion: This study concluded that bidara Arabic leaf extract has an antibacterial content that can inhibit the growth of Staphylococcus aureus bacteria.
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