Perbandingan proliferasi sel odontoblas menggunakan Mineral Trioxide Aggregate (MTA) dan biodentine secara in vitro
Kata Kunci:
Biodentine, odontoblast cell proliferation, Mineral Trioxide Aggregate (MTA)Abstrak
Introduction: Pulpitis is one of the dental and oral diseases whose prevalence is quite high, so it needs attention. In cases like this, pulp capping treatment must be carried out immediately. One of the requirements for pulp capping material is to form reparative dentin. Mineral Trioxide Aggregate (MTA) is widely used as a material for pulp capping because of its ability to form dentin bridges and also has good biocompatibility with the oral cavity. Biodentine can replace lost dentin structures, as a pulp capping material both direct and indirect, for restoration in secondary caries, and apexification. Purpose: The purpose of this study was to determine the proliferation ratio of the number of Odontoblast cells using MTA and Biodentine. Method: The method of this study was an experimental laboratory consisting of 2 groups that were given treatment, namely MTA and Biodentine while odontoblast cells were without treatment as a control. Before being treated, odontoblast cells (cell line) as samples were activated and subcultured first then treated for fourteen days using the MTT assay method, and the results of data analysis were read using a 595 nm wave ELISA reader. Result: The results showed a difference in the amount of odontoblast cell proliferation between the control group MTA and Biodentine. Conclusion: This study concludes that Biodentine has the highest amount of cell proliferation compared to Mineral Trioxide Aggregate.
Referensi
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