EFEKTIFITAS SALEP EKSTRAK GETAH POHON PISANG AMBON (Musa Paradisiaca V ar.Sapientum) TERHADAP KEPADATAN KOLAGEN DALAM MEMPERCEPAT PENYEMBUHAN LUKA INSISI TIKUS GALUR WISTAR (Rattus novergicus)
Kata Kunci:
incision wounds, Ambon banana trees, ointment, Wistar ratsAbstrak
Introduction: Banana plants are one of the plants that contain antibiotics. Wound healing is a biochemical process and cellular reactions involving synthetic cells, parenchyma, connective tissue, proliferation, migration, tissue regeneration. The wound healing process itself is influenced by several factors such as systemic diseases, drugs, smoking, diet, age, and so on. The purpose of this study was to provide analytical results related to the process of healing incision wounds in Wistar rats through the role of collagen density from Ambon banana sap extract in the form of ointment.
Method: The type of research used was an in vivo laboratory experiment.
Results: The results of the hypothesis test obtained a p-value <0.000, so the conclusion drawn was that there was a significant difference in collagen density in each group. The results of the Man-Whitney further test showed that there was a significant difference in effectiveness between the Ambon banana sap extract ointment with a concentration of 50% with Adeps lanae and Vaseline Album (K0), and there was no difference in effectiveness with povidone iodine ointment (K1).
Conclusion: Conclusion drawn from healing of incision wounds in Wistar rats can use an indicator of increased collagen density obtained from 50% Ambon banana tree sap extract and there is no significant difference in the increase in collagen density in the positive control of povidone iodine
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