STUDI IN VITRO PERBANDINGAN DAYA HAMBAT PASTA GIGI PROPOLIS DENGAN PASTA GIGI NANO PROPOLIS 2,5% TERHADAP JUMLAH KOLONI BAKTERI STREPTOCOCCUS MUTANS
Kata Kunci:
Streptococcus mutans, Nano propolis Toothpaste, Inhibitory PowerAbstrak
Orthodontic appliance users find it difficult to maintain oral hygiene during treatment because there are orthodontic components such as brackets, archwires, and elastics which prevent the toothbrush from reaching the proximal part of the tooth, causing dental caries. Nanoparticles are solid colloidal particles with diameters ranging from 1-1000 nm. One way that can be done to make nanoparticles is by using the ionic gelation method with chitosan precursors and NaTPP. The aim of this study was to make nano propolis toothpaste and find out whether nano propolis toothpaste has antibacterial inhibition against the growth of Streptococcus mutans compared to toothpaste. propolis on the market. The research method used was laboratory experimental research using the posttest-only control group design. This study was divided into 4 treatment groups, namely nano propolis toothpaste 2.5%, propolis toothpaste on the market, Chlorhexidine gluconate 0.2% as a positive control, and distilled water as a negative control. Antibacterial inhibition test using the disc diffusion method. The results of this study showed a significant difference. The mean zone of inhibition of Streptococcus mutans growth on nano propolis toothpaste was 14.5 mm, propolis toothpaste on the market was 8.8 mm, while the inhibition zone formed by 0.2% Chlorhexidine gluconate was 17.8 mm and 0 mm of distilled water. The conclusion of this study is that nano propolis toothpaste has antibacterial inhibition against the growth of Streptococcus mutans bacteria.
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