Pengaruh ekstrak daun ungu (Graptophyllum pictum l. Griff) terhadap pertumbuhan bakteri streptococcus sobrinus pada karies gigi anak
Kata Kunci:
dental caries, purple leaf, sterptococcus sobrinusAbstrak
Introduction: Dental caries is a dental and oral health problem that often occurs and can be experienced by various age groups, especially children. The dental caries process cause by acids from carbohydrate fermentation, which causes demineralization of the hard tissue of the teeth by bacteria. The main cariogenic bacteria in the process of caries pathogenesis is Streptococcus mutans, which Streptococcus sobrinus can be more cariogenic than Streptococcus mutans. A safer alternative ingredient for preventing dental caries is purple leaf (Graptophyllum pictum L. Griff). Purpose: This study aims to determine the differences in antibacterial concentration of purple leaf extract on the growth of Streptococcus sobrinus. The concentrations of purple leaf extract (Graptophyllum pictum L. Griff) used in this research were 5%, 10%, and 15%.
Methode: The research method used was Kirby-Baurer or disk diffusion to determine the inhibitory power of purple leaf extract against Streptococcus sobrinus bacteria.
Result: The results showed that the mean zone of inhibition for the positive control was 19.40, the 5% extract concentration was 5.51, the 10% concentration was 12.25, and the 15% concentration was 14.64. Based on the results, purple leaf extract with concentrations of 5%, 10%, and 15% had different inhibitory effects on the growth of Streptococcus sobrinus, with a purple leaf extract concentration of 15% having the greatest inhibitory effect on the growth of Streptococcus sobrinus.
Referensi
Notoatmodjo S. Promosi Kesehatan dan Perilaku Kesehatan. Jakarta: Rineka Cipta;
Kidd EA, Bechal SJ. Dasar Dasar Karies. Jakarta: EGC.; 1991.
Dianawati N, Setyarini W, Widjiastuti I, Ridwan RD, Kuntaman K. The distribution of Streptococcus mutans and Streptococcus sobrinus in children with dental caries severity level. Dent J. 2020;53(1):36–9.
Okada M, Taniguchi Y, Hayashi F, Doi T, Suzuki J, Sugai M, et al. Late Established Mutans Streptococci in Children over 3 Years Old. Int J Dent. 2010;2010:1–5.
Conrads G, de Soet JJ, Song L, Henne K, Sztajer H, Wagner-Döbler I, et al. Comparing the cariogenic species Streptococcus sobrinus and S. mutans on whole genome level. J Oral Microbiol. 2014;6(1):1–13.
Kusumaningsih T, Sidarningsih, Putra AA, Aljunaid M. Antibacterial Differences Effect between Purple Leaves (Graptophyllum Pictum (L) Griff.) 70% And 96% Ethanol Extract Against Aggregatibacter Actinomycetemcomittans Bacteria. J Int Dent Med Res. 2021;14(2):519–24.
Rahman. Uji Efek Antibakteri Ekstrak Daun Wungu (Graptophylum Pictum Griff) Asal Kabupaten Enrtekang Terhadap Pertumbuhan Streptococcus mutans. J Media Anal Kesehat. 2017;8(2):111.
Kurniawati A. Pengaruh kumur ekstrak daun ungu terhadap jumlah bakteri dalam saliva. Stomatognatic (JKG Unej). 2018;15(2):43–6.
Matsumoto-Nakano M. Role of Streptococcus mutans surface proteins for biofilm formation. Jpn Dent Sci Rev [Internet]. 2018;54(1):22–9. Available from: http://dx.doi.org/10.1016/j.jdsr.2017.08.002
Permatasari RN, Santoso O. Pengaruh Ekstrak Daun Kemangi (Ocimum Basilicum Linn) Pada Berbagai Konsentrasi Terhadap Viabilitas Bakteri Streptococcus Mutans. Universitas Diponegoro; 2017.
Wungsu ND. Perbedaan Daya Antibakteri Ekstrak Etanol 70% Dan Ekstrak Etanol 96% Daun Ungu Graptophyllum Pictum (L) Griff Terhadap Streptococcus Mutans. Universitas Airlangga; 2018.
Dewi TP. In vitro study comparison of purple leaf extract as denture cleanser at different concentration towards S. mutans growth on flexible denture. Bali Med J. 2020;9(3):716–20.
Rahmawatiani A, Mayasari D, Narsa AC. Kajian Literatur: Aktivitas Antibakteri Ekstrak Herba Suruhan (Peperomia pellucida L.). Proceeding Mulawarman Pharm Conf. 2020;12:117–24.
Dhywinanda DE, Dien SN, Chairuly HD, Sakti GR, Tandra RJRF, Kartikasari N, et al. Essential of Graptophyllum pictum for the medical and dental purposes. Indones J Dent Med. 2023;6(2):83–8.
