UJI DAYA HAMBAT EKSTRAK DAUN JARAK PAGAR (Jatropha curcas L.) TERHADAP PERTUMBUHAN BAKTERI Aggregatibacter actinomycetemcomitans SECARA IN VITRO
Kata Kunci:
Aggregatibacter actinomycetemcomitans, Jatropha leaf, InhibitionAbstrak
Introduction: Aggressive periodontitis is a disease of the periodontal tissue caused by bacteria, one of which is the Aggregatibacter actinomycetemcomitans bacteria. The leaves of jatropha (Jatropha curcas L.) contain active antibacterial substances, namely saponins, phenols, steroids, terpenoids, alkaloids, flavonoids and tannins. The purpose of this study was to determine the inhibitory power of jatropha (Jatropha curcas L.) leaf extract against the bacteria Aggregatibacter actinomycetemcomitans in vitro.
Methods: This research is a laboratory experimental research with a true experimental research type in vitro with a Post-Test Only Control Group Design. This test used 25 samples with 5 treatment groups and five repetitions. The treatments given were jatropha (Jatropha curcas L.) leaf extract with concentrations of 25%, 50%, and 100%, Tetracycline as a positive control and 96% etanol as a negative control.
Results: The results showed that the inhibitory power of jatropha (Jatropha curcas L.) leaf extract at a concentration of 25% had an average of 10.2 mm, 50% had an average of 12.64 mm and 100% had an average of 15.14 mm. against the growth of Aggregatibacter actinomycetemcomitans bacteria. Concentrations of 50% and 100% include strong inhibitory power against the Aggregatibacter actinomycetemcomitans bacteria, while the 25% concentration includes moderate inhibitory power.
Conclusion: All concentrations can inhibit Aggregatibacter actinomycetemcomitans, but the most effective is the 100% concentration.
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