Uji Alergi Ekstrak Batang Serai Wangi Pada Mencit Menggunakan Globally Harmonized System (GHS)
Kata Kunci:
Lemongrass stem extract, allergy test, miceAbstrak
Lemongrass stems are used by the public as a medicine for sore throats, to reduce fever, to overcome digestive problems, as an antioxidant, anti-inflammatory and anti-cancer, so you need to know the safety of its use. Allergies are hypersensitivity reactions that are initiated by immunological mechanisms, namely due to induction by Immunoglobulin E (IgE) which is specific to certain allergens that bind to mast cells. Allergy testing is a skin examination or blood test procedure carried out to determine substances or materials that can cause allergic reactions. One of the allergy diagnostics is a skin examination. In allergy testing using 5 mice, given topically on the backs of mice in the form of a gel and observed for allergic reactions for 24 hours. In allergy testing using the Organization for Economic Cooperation and Development (OECD) method. In this study using OECD Guideline No. 404. The results of the allergy test are included in the non-irritant category. In allergy testing using the Wilcoxon signed ranks test.
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